Abstract

This study examines the carbon footprint of the diets of athletes aged 15 to 30 who participate in various sports. To examine the total carbon emission, the study calculated the carbon footprints of the various food groups and their sub-food groups, including cereals, meat, dairy products, vegetables, fruits, confectioneries, sugar, fats, and oils. Athletes in India have high carbon emissions associated with cereals and dairy products because of their high-energy dietary needs. Cereals and dairy products are often the staple food in the Indian diet and are used as an important source of energy for athletes. These food sources are highly processed and require large amounts of energy and resources to produce, thus leading to high carbon emissions. The Calculations of the carbon footprint of food consumed by the participants in the study were done using the global warming potential formula with the help of the databases available online in different research articles which have compiled together the carbon footprint scores of different food items.

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carbon footprint , sustainable environment, Athletes diet, sports nutrition, environment

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Ropinirole HCL is a para-sympathomimetic or cholinergic agent, used to treat mild to moderate dementia caused by Parkinson disease. It is subjected to an extensive hepatic first pass metabolism with systemic bioavailability of 36%. Its short half-life being 3-4 hours. The objective of the present study is to develop sustained release mucoadhesive buccal tablet for Ropinirole HCL to overcome poor bioavailability (below 50%) due to extensive first pass metabolism, poor permeability from the GIT and shorter half-life (2-6 hr.) by reducing the dosing frequency. Direct compression method was used to prepare buccal tablet. The prepared formulations were characterized for pre & post compression studies. The results of FTIR study revealed that there is no physical or chemical interaction between drug and polymer. Formulation Batch C-7 was selected as optimized batch which contain Ropinirole HCL (1 mg), HPMC-K4M (120 mg), HPMC -K100 (140mg), Mannitol (100 mg), Magnesium stearate 2%. The optimized batch was showed evaluation result as, Weight Variation (251.6�1.712), Hardness (8.36�0.05) kg/cm2, Diameter (12.27�0.115), Thickness (3.12�0.002) mm, Friability (0.50�0.01), Drug Content (98.93�0.92) %, Muccoadhesive strength (38.34�0.205) gm and Muccoadhesive force studies (3.76�0.136) Dyne and cumulative drug release for 8 hours (43.60�0.122). It was concluded that the prepared of Sustained release Muccoadhesive Buccal tablet of Ropinirole HCL may prove to be potential candidate for safe and effective Sustained release drug delivery over an extended period of time which can reduce dosing frequency.

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Key World: Buccal Tablet, Polymers, Muccoadhesive tablets, Buccal Administration.

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Experiences of Guidance Designates in the Implementation of School Guidance Services: A Phenomenological Case Study DR. LOLITA A. DULAY-University Assistant Professor IV MS. MARIEL FE L. PITONANG- Teacher Institution: Bukidnon State University Address: Malaybalay City, Bukidnon, Mindanao, Philippines, 8700 Email address: lolitadulay@buksu.edu.ph Contact Number: 09357066271 Abstract This study explored the experiences of the school guidance designates in the implementation of guidance services in Impasugong 1 district, Division of Bukidnon during the school year 2019-2020. The qualitative narrative inquiry method of research by Clandinin and Huber (2010) served as the methodology of the study. There were seven guidance designates purposively chosen as the participants of the study. An in-depth interview using the interview guide questions gathered the significant information. The analysis made use of Creswell�s (2017) model. Findings revealed that the guidance designates encountered barriers and difficulties in the implementation of guidance services. Among the seven services, on individual inventory there were three emergent themes discovered experienced Difficulty in the implementation due to lack of knowledge on individual inventory services, Hindrances in the implementation due to multitasking of the guidance designates, and Insufficient support for the guidance services. While in the implementation of Information services there were also the emergent themes explored they Struggle to implement due to lack of information in conducting the services, Overlapping of responsibilities and the Insufficient support system. While in terms of implementing guidance counselling the emergent themes were as follows, they encountered problems having no background knowledge and information in conducting proper counseling techniques among learners, Difficulty in conducting counseling due to insufficient support system and the absence of facilities conducive for counselling among learners and The guidance designate should be qualified with enough background information and units in master in guidance. Hence, in Assessment and appraisal they experienced, Struggles to conduct assessment and appraisal among learners due to a lack of background and enough information about the services, and they need training and orientation on assessment and appraisal to effectively implement. As well as on referral services, the guidance designates experienced is not properly and effectively implemented due to no background and enough information about the services, and in the follow-up services they encountered problems with the learners and parents� schedule and cooperation during follow-up since parents and working for a living and on Consultation the designates has problems encountered in the conduct of an effective and proper consultation among the learners due to lack of knowledge and masters in guidance units. The researcher designed a proposed intervention plan to strengthen the school guidance program and services. Key words: Experiences, Guidance Designates, Guidance Services, A Phenomenological Case Study

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Key words: Experiences, Guidance Designates, Guidance Services, A Phenomenological Case Study

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????? ???? ???????

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The convergence of Internet of Things (IoT) and machine learning has revolutionized various domains, and smart farming is no exception. Smart farming involves the integration of IoT devices and sensors with traditional agricultural practices, enabling efficient and sustainable crop management. This paper presents an overview of IoT and machine learning approaches for classification in smart farming. IoT technology enables the collection of vast amounts of data from various sources, such as soil moisture sensors, weather stations, and crop health monitors. This data provides valuable insights into the condition of crops and the environment. Machine learning algorithms, on the other hand, facilitate the analysis and interpretation of this data, enabling farmers to make informed decisions and optimize farming practices. Classification is a fundamental task in smart farming, as it involves categorizing different aspects of agricultural operations, such as plant diseases, soil conditions, and crop growth stages. IoT devices continuously generate data streams that capture temporal and spatial information. Machine learning algorithms, particularly those based on deep learning, can effectively process and classify this data, enabling early detection of plant diseases, accurate soil analysis, and precise prediction of crop growth.

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IoT, Machine Learning Algorithms, Agriculture, etc

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Age and gender detection are important tasks in computer vision with numerous applications in various fields such as marketing, healthcare, and security. In recent years, the use of artificial intelligence (AI) techniques has greatly enhanced the accuracy of age and gender detection systems. This paper provides a comprehensive overview of age and gender detection models, their evaluation and selection, implementation and deployment, as well as ethical and legal considerations. The paper also explores the applications of age and gender detection in different industries and presents a step-by-step guide for building and deploying age and gender detection models. The future scope of age and gender detection technology is discussed, along with its potential benefits and challenges.

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Age detection, Gender detection, Computer vision, Artificial intelligence, Deep learning, Machine learning, Model evaluation, Model selection, Implementation, Deployment, Ethics, Legal considerations, Applications.

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In the current period, in India religion and language are most perceptive issues in our country because on this basis the people take over other society. The Constitution of India used the word Minority� in the Articles No. 29 and 30 and 350A and 350 B. It means the people of the leading group or community are numerically high (which is called as majority) and the other group is called as minority. The concept of minority has been escalating ahead of the boundaries of the state and nation. It basically speaks about two kinds of minorities in India which are religious and linguistic. This point of view has created various problems related to the Minority and their rights. Many high courts and Supreme Court judgments have discussed the concept and criteria of minority status and their rights.An analysis of the identification of the Linguistic Minorities problems and rights and government schemes reflected in the peer-reviewed validly published literature has been done in this study reviewing the individual studies and methods of several articles or papers or books. Three broad artificial categories namely - Linguistic Minority, socio- culture and identity crisis historical precept have been constructed for systematic addressing of the relevant problems identified by the researchers of those studies. Together, the propositions provide a scheme for understanding and categorizing what is known and still needs to be known about the problems of the linguistic minorities, a framework for probing the significant theoretical and substantive issues underlying the findings that emerge from the various angles of study already performed. It has been found that culture is communicated and transmitted through the educator�s approach to teaching and how learner experiences it. It can contribute either positively or negatively as far as ethics and linguistic minorities are concerned. Educators then have a liability to consult local culture while being conscious of individual context and humanity in an effort to avoid oppression. Culture, cultural identity, language , status and population are required to be strictly interpreted in order to understand the problems of Linguistic Minorities.

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Concept, Minority, linguistic. Rights. Religious , educator, problem, status,india , culture.

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�A STUDY ON LIVED EXPERIENCE OF HEALTH PROFESSIONALS WORKING IN JUVENILE DELINQUENCY CENTRE IN SELECTED AREA OF ROHTAS.�

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�A STUDY ON LIVED EXPERIENCE OF HEALTH PROFESSIONALS WORKING IN JUVENILE DELINQUENCY CENTRE IN SELECTED AREA OF ROHTAS.�

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In the present investigation, the Rajmahal sand was selected as refractory raw material, and its various properties, such as AFS fineness number, specific surface area grain shape and texture base permeability, moisture, and clay content density for characterization, among the binder phenolic and alkyd no-bake resins, were characterized by testing its viscosity. Specific gravity, solid, and ash content.In the sand stage of investigation standard specimen was prepared with the characterized sand, and different proportions of resin constituents and composition of the mix were optimized for maximum strength. The standard specimen were made with optimum composition, and these were used for various room temperature test like strength development friability characteristics, working time pattern strip time as well as retained strength.The carbon dioxide sodium silicate process is one of the oldest processes. However, it is still in use due to the many advantages like no necessity of drying or baking, no carbon pick up from mould on casting surface and no smoke or gas evolution during pouring and shake out. Also the essential material and basic capital costs of this process lower than alternative process and it is relatively environmental safe. The cores and moulds prepared in foundry must have sufficient compressive strength for easy handling and also to avoid erosion of mould surface at corners during pouring of metal.The compressive strength of CO2 silicate bonded sand is affected by parameters.In the present investigations the effect of certain variable such as binder per cent, flow rate of CO2 gas, gassing time and holding time on compressive strength have been studied.

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Binder,Moulding,compressive,sand

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For around 2500 years, the Justicia adathoda(L.), Nees have been used in indigenous medical systems all across the world. Justicia adathoda(L.) is commonly used in the Unani, an ayurvedic system of medicine. It was used traditionally to treat a variety of ailments and had strong pharmacological action, notably for bacterial infections, cough, bronchial infections, heart diseases reproductive abnormalities etc. Justicia adathoda (L.) contains a variety of constituents such as alkaloids, steroids, flavonoids, tannins, saponins, and so on. The plant’s active constituents include maiontone, l-vasicinone, vasicinolone, deoxyvasicine, vasicine, and vasicinol among all other constituents. This review offers current information on the phytoconstituents found in Justicia adathoda(L.), their pharmacological activities, ethanomedicinal applications, numerous formulations and their indications, pharmacokinetic profile, precautions, and warnings while using this plant. According to the critical evaluation, it was determined that there is insufficient scientific data to explain how the extract may be detrimental to humans, particularly women while they are pregnant. Key information on conventional use, in addition to toxicological investigation was examined for accuracy, relevance, significance, and reliability in the overall assessment of the safety of Justicia adathoda(L.). Many clinical trials on Justicia adathoda(L.) herbal formulations are being undertaken all over the world (L.). This review offers significant evidence from phytochemical and pharmacological investigations that show Justicia adathoda(L.) is a distinctive indigenous plant of India with a commercialiazed reputation and may thus be encourage for diverse applications such as medicinal and other potential uses.

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Justicia adathoda (L.), active ingredients, pharmacological activities, versatile and safe native plant of India.

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This dissertation compares the increasing issues in international commercial arbitration�s conflict of laws issues while determining the applicable law in the arbitration agreement, specifically when the governing law is absent. The framework is based on the chronology of arbitration, which goes from the arbitration agreement through the actual procedures, and then into court processes involving arbitration with different systems of governing laws, and their approaches. There are now opposing viewpoints on whether the law relevant to the arbitration agreement should be the law of the arbitral seat or the law of the primary contract. The main goal here is to not only determine the conflict of laws issues in arbitration agreements but also to critically analyse them and provide better alternative approaches. This dissertation seeks to examine the extent to which the two main approaches are executed in practice compared to the uncertainty that can result in their application, while determining which approach is accurate when the applicable governing law is absent. This dissertation concludes with a view of current developments to answer the conflict of laws issues when the governing law is missing, addressed with relevant case law, and legal approaches finally linked to practical practice.

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International Arbitration, International Commercial Law, Applicable Law, Conflict of Laws, International Commercial Arbitration, Arbitral Agreement

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The company manufactures confectionery products. It provides candies, chocolate Products & Services: candies, chocolate, chewing gum,etc. In 2003, while the overall top line for the Indian operations of the global confectionery major Perfetti Van Melle was showing consistently upward trend (around 14% CAGR), the Gums line of the same was a drag for the company and was not able to make a positive contribution to the company bottom-line. In fact, Gums business grew only 3 per cent last fiscal. The line has been faced with stagnant sales and was unable to utilise the allocated plant capacity. The Divisional Head of the Line, along with his team was faced with this grave situation and was frantically looking for a break.

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Perfetti Van Melle’s innovations provide ample proof of the effectiveness of its product customization strategy and its attention to consumer demand.

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ABSTRACT Cardiovascular diseases are considered as the most life-threatening syndromes with the highestmortality rate globally. Over a period of time, they have become very common and are now overstretchingthe healthcare systems of countries. The major factors of cardiovascular diseases are high blood pressure,family history, stress, age, gender, cholesterol, Body Mass Index (BMI), and unhealthy lifestyle. Based onthese factors, researchers have proposed various approaches for early diagnosis. However, the accuracyof proposed techniques and approaches needs certain improvements due to the inherent criticality andlife threatening risks of cardiovascular diseases. In this article, a MaLCaDD (Machine Learning basedCardiovascular Disease Diagnosis) framework is proposed for the effective prediction of cardiovasculardiseases with high precision. Particularly, the framework first deals with the missing values (via meanreplacement technique) and data imbalance (via Synthetic Minority Over-sampling Technique - SMOTE).Subsequently, Feature Importance technique is utilized for feature selection. Finally, an ensemble of LogisticRegression and K-Nearest Neighbor (KNN) classifiers is proposed for prediction with higher accuracy.The validation of framework is performed through three benchmark datasets (i.e. Framingham, HearDisease and Cleveland) and the accuracies of 99.1%, 98.0% and 95.5 % are achieved respectively. Finally,the comparative analysis proves that MaLCaDD predictions are more accurate (with reduced set of features)as compared to the existing state-of-the-art approaches. Therefore, MaLCaDD is highly reliable and can beapplied in real environment for the early diagnosis of cardiovascular diseases.

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Cardiovascular diseases, machine learning, cardiovascular prediction, ensemble, SMOTE, feature importance, MaLCaDD framework.

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The screening of patients for signs of oral cancer and potentially malignant disorders has always relied upon the conventional oral examination. Several commercially available conventional diagnostic aids and adjunctive advanced techniques potentially assist in the screening of occult cancerous change or to assess the biologic potential of clinically ab-normal mucosal lesions. This manuscript systematically and critically reviews the literature associated with recent technological advances in oral cancer and potentially malignant dis-order screening for a more reliable and accurate diagnosis.

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Chemiluminescence, Pre-malignant, Oral cancer, Velscope

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The purpose of this study was to acquire a better understanding of the issues and challenges that biracial students confronted as they navigated the Philippine K-12 school system while developing a strong sense of self and Filipino nationalism. The goal of this research was to look into biracial students’ experiences in the Philippine educational system. As an output of the study, a cultural diversity program was proposed. The research design used was qualitative with phenomenology as approach. Using the interpretative phenomenological approach, the study generated ten emerging themes: which were Positive and Negative Experiences as Biracial Students; Cultural Awareness, Language, Socialization and Travel Opportunities; Language Barrier, Religion, Cultural Differences and Racism; Language Learning, Socialization, Being-Yourself and Open-mindedness; Pride, Love, and Respect for Filipinos, Their Culture and Tradition; Being Proud and Respectful of Filipino Culture, Values and History; Family and Friends, Studying in the Philippines and Exposure to Filipino Culture; Influence on Filipino Identity and Gained Different Ideas about the Filipinos and the Philippines; Gained Knowledge about the Filipinos, Their Heroes, History and Cultural Differences and Language Learning, Cultural Awareness and Social Development Program. The major findings strongly suggested that teachers and students must broaden their knowledge and students’ relationships with other people to incorporate meaningful and authentic learning experiences. The second key result was that the most powerful factors that built Filipino nationalism can be utilized both within and outside the classroom. Furthermore, it was vital for parents to teach their multiracial children about their race at a young age.

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Biracial Student, Filipino Nationalism, Pride, Love, Respect

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The traffic has been transformed into the difficult structure in points of designing and managing by the reason of increasing number of vehicles. This situation has discovered road accidents problem, influenced public. health and country economy and done the studies on solution of the problem. Large, calibrated data agglomerations have increased by the reasons of the technological improvements and data storage with low cost. Arising the need of accession to information from this large, calibrated data obtained the corner stone of the data. mining. In this study, assignment of the most compatible machine learning classification techniques for road accidents estimation by data mining has been intended. There are several problems with current practices for prevention of the accidents occurred in the localities. The database we will use is available officially by many institutes and government websites. The data collected. will be analyzed, integrated, and grouped together based on different constraints using the best suited algorithm. This estimation will be helpful for collecting data and it shows the risk in a particular area is high or low. We have made use of data mining techniques in developing an accident prediction model using logistic. regression algorithm and gradient boosting algorithm. Bangalore road accident datasets for the years 2014 to 2017 available on the internet have been made use for this study.

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MECHINE LEARNING, PYTHON, LOGISTIC REGRESSION ALGORITHM, GRADIENT BOOSTING ALGORITHM

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Automated Vending Technology has become legacy now. Digitized version of Automated Vending Technology is termed as Autonomous Vending Technology. Intelligence added to has made it an iAutonomous Vending Technology. Using this Technology, Internet based retailing has become possible. Human intervention needed only at refilling part. Other than that, all the associated operations are taken care by the machine itself. It helps every common man to start or involve in retail sales based business at any moment. Biggest challenge in doing a retail business in accountability of stock, periodic monitoring of product availability, failure handling, managing supply chain, etc� But now, we have made all this operations into a robotic operations. Also, this helps to dispense products with any credentials.

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AVM VendingMachine AutomatedVendingMachine SmartVendingMachine

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Dandruff is a random scalp disorder which is caused by the multiple different organisms of the family of Malassezia. The most efficient way to control dandruff is shampooing the scalp with the frequent intervals. Dandruff is a common scalp disease, that affects above 50% of the earth�s population. The adults are the major affected people of seborrheic dermatitis. Dandruff is the major initial problem that induce the hair fall. The causative organism of dandruff is Malassezia furfur, it is a lipophilic, basidiomycetous fungi. As dandruff is seen in worldwide, it needs an effective treatment to overcome from the disorder. The numerous types of commercial antidandruff shampoos were used to treat dandruff as it contains some antifungal agents. As these shampoos has high concentrations of chemicals, they cause many side effects. Therefore, the polyherbal extracts prepared from different herbal plant materials were used to overcome from this problem. The antifungal activity of commercial antidandruff shampoos and the polyherbal extract shampoos were compared. The polyherbal hair care cosmetic was prepared by the different herbal plant materials, the extracts of soap pod, neem leaves, henna, hibiscus leaves, lemon peel, amla, curry leaves, green gram, Bengal gram, extract of rose petal, fenugreek seeds were dried and used as a natural polyherbal shampoo, which does not have any side effects. The antifungal assay was studied under the agar well diffusion and disc diffusion method. The phytochemical analysis of the polyherbal plant extract were carried out in this study.

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Dandruff, Malassezia furfur, Polyherbal extract, Synthetic shampoo

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ABSTRACT The present study was aimed to assess the effect of structured educational programme regarding prevention of ventilator associated pneumonia among staff nurses in P.K Das Institute of Medical Sciences. The objectives of this study were to assess the level of knowledge regarding prevention of ventilator associated pneumonia among staff nurses, find the effectiveness of structured educational programme regarding prevention of ventilator associated pneumonia among staff nurses and find the association between pretest level of knowledge with selected demographic variables. The research approach was quantitative and the research design adopted was one group pre-test post-test research design. Sixty staff nurses selected by purposive sampling technique. Data was collected using structured questionnaire. The result shows that the obtained �t� value for nursing staff knowledge of ventilator associated pneumonia value in 16.61 significant at 0.05 level. It is inferred that the nursing staffs exposed to the structured educational programme had significant increase in post test knowledge. The Chi square test value shows that there is no association between level of knowledge with the demographic variables such as age, sex, educational qualification, present working area, year of experience and previous knowledge. Key words: Structured educational programme, Ventilator, Pneumonia

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Key words: Structured educational programme, Ventilator, Pneumonia

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Self-compacting concrete is the very flowable, non-isolating solid that can spread into put, fill formwork, and embody even the most congested support by methods for its own weight, with practically no vibration. It conveys these appealing advantages while keeping up or improving all of standard mechanical and solidness qualities of cement. Changes in accordance with customary blend plans and the utilization of super plasticizers make this solid that can meet stream execution necessities. The self-compacting concrete is perfect to be utilized for throwing vigorously fortified areas or be set where there can be no entrance to vibrators for compaction and in complex states of formwork which may some way or another be difficult to cast, giving a far better surface than regular concrete. Self-compacting concrete, likewise alluded to as self-uniting concrete, can stream and combine under its own particular weight and is deaerated totally while streaming in the formwork The use of quartz sand as replacement for sand is an economical solution for making the concrete resistant to weathering. The Study Includes a concrete mix design procedure for partial replacement of sand with quartz sand and addition of PP Fibers by volume of cement. Present method was performed to evaluate the additional compressive, and Split Tensile Strength, flexural strength over conventional concrete. in which sand is replaced with 0%, 5%, 10%, 15%, 20%, 25%, by weight with 1% viscosity modifying agent. Compressive, Split Tensile and flexural strength tests were carried out to evaluate the strength properties of concrete at the age of 7, 14 and 28 days. Mix Proportions 0%QS+0.6PPF+1%VMA,5%QS+0.6PPF+1%VMA,10%QS+0.6PPF+1%VMA,15%QS+0.6PPF+1%VMA, 20%QS+0.6PPF+1%VMA,25 %QS+0.6PPF+1%VMA.

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Self Compacting Concrete, M30 Concrete, Quartz Sand.

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Concrete has the largest production of all manmade materials. It is a composite mixture containing cement paste and aggregates as its main components. Nowadays, common Cement is quite expensive so the main emphasis of this study is to find an alternative of Cement.. Concrete is the most important component used in the construction industry throughout the world. Due to excessive mining, natural resources are getting exhausted results in increase in scour depth and sometimes flood possibility. Thus, it is becoming inevitable to use alternative material in concrete. The various studies have been done using either stone power or marble powder as a replacement of sand. To reduce the solid waste minimization and waste recovery, a combination of Bethamcherla Stone Powder has been attempted in this study. The percentages of Bethamcherla Stone Powder added to replace Cement were 5%, 10%, 15%, 20% and 25% of the Cement by weight. In this present examination had been made to talk about the Workability, Compressive Strength, Split Strength, Flexural quality of concrete by supplanting Cement with Bethamcherla Stone Powder with various substitution levels 0%BSP, 5%BSP, 10%BSP, 15%BSP, 20%BSP,25%BSP for M20 Grade of Concrete.

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Bethamcherla Stone Powder, M20 Grade Concrete, Split Rigidity, Flexural Strength.

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A simple, sensitive and accurate Development and validation of analytical method for estimation of Efonidipine hydrochloride, Ethanolate and Chlorthalidone in synthetic. A reversed-phase high performance liquid chromatography method is developed and validated for the determination of three drugs. With the help of RP- HPLC it gives us to good resolution and better separation of three drugs. The separation was conducted by using Cybersil C18 column (250mm x 4.6mm x 5?m) with mobile phase consisting Potassium dihydrogen phosphate: Methanol: Acetonitrile (30:30:40 v/v/v) (pH :3). The mobile phase was delivered at flow rate of 1.0 ml/min. m. During the forced degradation studies, Efonidipine showed maximum degradation (10 %) under oxidative stress followed by 8 % photodegradation. The drug showed lower degradation under acid, base and thermal stress conditions, to the extent of 4 %, 3 % and 6 % respectively. It was also observed that the retention time of the degradant under photolytic and oxidative degradation were the same probably due to the formation of the same product. Therefore, proposed method can be successfully used for routine analysis of Efonidipine hydrochloride, Ethanolate and Chlorthalidone in bulk as well as synthetic mixture.

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Efonidipine (EFO),Telmisartan (TEL), and Chlorthalidone(CTD),reversed�phase highperformance liquid chromatography (RP-HPLC)

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A STUDY ON CUSTOMER SATISFACTION TOWARDS ROYAL ENFIELD BIKES DLEHI NCR

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customer satisfaction

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CONSUMER BEHAVIOUR TOWARDS ONLINE SHOPPING DURING COVID 19

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consumer behaviour in online shopping

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Asthma and Chronic Obstructive Pulmonary Disease are airway obstructive disease that causes both morbidity and mortality in the general population. Often it becomes difficult to know the cause of airway obstruction as sometimes asthma mimics chronic obstructive pulmonary disease. The well-defined feature that allows us to have a differential diagnosis is fixed airflow obstruction in asthma from COPD. Obstructive airway disease falls under an umbrella term due to the presence of a heterogeneous population and Asthma-COPD phenotype or Overlap syndrome (ACOS). Also, recent studies have shown that neither asthma nor COPD are single diseases but rather syndromes due presence of multiple endotypes and phenotypes. An Eosinophilic phenotype is a distinct form of type 2 airway obstructive disease in Asthma and whereas in COPD it is traditionally associated with neutrophilic infiltration in bronchi. But recent studies have shown that around 25-40 % of patients have severe exacerbation and decline of lung function with higher levels of eosinophil in COPD. Therefore this helps to personalize a targeted therapy based on traits and the role of ICS in this kind of phenotype.

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Airway obstruction, Asthma, COPD, Eosinophilic phenotype, ACOS syndrome.

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MARKETING STRATEGY OF MAHINDRA AUTOMOBILE

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MARKETING STRATEGY IN MAHINDRA

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The present study has been done to review the various techniques that has been used for the examination of parts of a skeletal remain that contribute towards developing a biological profile of the person. Methods for age estimation, stature estimation, gender estimation, and ancestry assessment has been discussed along with their limitations, and suggestions have also been made on how the challenges that are posed towards the accuracy and reliability of such methods may be tackled with. Emerging technologies and methods for the identification of skeletal remains have also been discussed, and the effect of various traumas on skeletal remains has additionally been studied, as these provide major clues to the cause of death. An attempt has also been made towards the end of the study to highlight areas of new research prospects and advancements that can help towards a better and more reliable positive identification of skeletal remains.

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Skeletal remains, Forensic anthropologists, Biological Profile, Age estimation, Stature estimation, Gender estimation, Ancestry assessment, Trauma.

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Creative Commons Attribution 4.0 and The Open Definition

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The human skeletal system becomes brittle, due to loss of bone density, whichcan lead to fractures and a compressed spinal column, thereby affecting posture and resulting pain in the back and the spine with increasing age. With alarming conditions, it affects other functions and organs in the body, causing associated symptoms of osteoporosis, constipation, degenerative arthritis, low back pain, insomnia, bladder and kidney weakness, frequent urination and dental problems.

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Rheumatoid Arthritis disease, Rickets Disease, Osteoporosis Disease, Osteomalacia Disease, Pagetis Disease, Frozen Shoulder Disease, Clavicle Fracture Disease, Trigger Finger Disease, Felty Syndrome Disease

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Creative Commons Attribution 4.0 and The Open Definition

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In order to prevent phishing, a new graphical tool defined to check the wireless router security and vulnerability in order to avoid unauthorized access by hackers. In the existing projects & works there are many programmers and researchers who use different commands manually and one by one. To make it simple and easy we have created a new graphical tool for this purpose. It combines both Airmon-ng, Airodump-ng, Aireply-ng and Air crack-ng. By running this tool will assert the wireless router and report the Net admin that the router is secured or not.

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Router, Security , Tool , Vulnerability

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Creative Commons Attribution 4.0 and The Open Definition

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BANKING FINANCIAL ANALYSIS AND INVESTMENT OPPORTUNITIES IN INDIAN BANKING INDUSTRIES

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FINANCIAL AND INVESTMENT RESEARCH

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Creative Commons Attribution 4.0 and The Open Definition

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BANKING SERVICES AND INVESTMENT OF PRODUCTS HDFC BANK

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RESEARCH ON NEW PRODUCTS

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�A STUDY AMONG AGGRESSION OF FOOTBALL AND HANDBALL PLAYERS OF INTER-UNIVERSITY LEVEL�.

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�A STUDY AMONG AGGRESSION OF FOOTBALL AND HANDBALL PLAYERS OF INTER-UNIVERSITY LEVEL�.

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This study aimed to investigate the potential of organic based waste material used in the form of Biostimulant and Biofertilizer. The contemporary research deals with the usage of fruit peels for efficient growth of plants and higher yield. Two different kinds of fruit peels such as banana and pomegranate were used. These fruit peels are highly rich in potassium, iron, calcium, zinc etc. Mustard seeds were used to test the utilization of fruit peel powder and extract as a natural growth enhancer. After 30 days of application of Biofertilizer plant growth was measured and the yield of mustard was counted.

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Biostimulant, Biofertilizer, Fruit peels, Mustard seeds.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Agriculture is being considered the most important sector of the Indian economy as it contributes almost about 33 per cent of the Gross Domestic Product (G.D.P.). It provides livelihood for about two thirds of the working force in the country. The total share of the agricultural products in the export earnings, both in primary as well processed forms, is very significant. The National Commission on Agriculture (1976) emphasized that, the agricultural sector has to grow at much faster rate than before not only for its own sake, but also for the sake of the Indian economy as a whole. Hence, the prosperity of the country entirely depends on the prosperity of the agricultural sector. Due to introduction of new agricultural technologies in India, has converted the nature of agriculture from traditional to modernization. The farmers intended towards the replacement of traditional methods of farming with the scientific, advanced and innovative forms of agriculture. Hence, the purchase of agricultural inputs and their application requires huge capital which is beyond the capacity of most of the Indian farmers. Therefore, farmers are being forced to depend upon borrowed funds. Basically, farmers are in the need of three types of credits such as short-term, medium-term and long-term credits. The short-term and medium-term credit requirements are met by the co-operative banking institutions like PACs, CCBs and SCBs whereas; long term credit requirements are being met by the Land Development Banks popularly known as LDBS and now they are called as Agriculture and Rural Development Banks .Significance of the study: The present study is intended to focus on the performance of the State Cooperative Agriculture and Rural Development Banks in India. It aims to assess the working performance of ARD Banks with respect to a few parameters of financial indicators such as Deposits, Investments, Advances, Borrowings, Recoveries .etc.The primary objective of this study was to analyze the performance of the financial indicators of State Cooperative Agriculture and Rural Development Banks in India. Methodology: This study is purely based on the secondary data. The secondary data were collected from the Annual reports of National Agricultural Cooperative Marketing Federation of India, Reports of National Cooperative Agriculture and Rural Development Banks Federation, Land Bank Journals, reports of the Statistical Department, Reports by the Registrar of Cooperative Societies and their websites. Reserve Bank of India�s Reports, journals and Periodicals etc. covering last ten years. Statistical tools and Techniques: The present study uses the appropriate tools and techniques to analyze the data. The descriptive statistics Mean, Median, Standard Deviation, . Compound Annual Growth Rate (CAGR), Annual Growth Rate and the Trend Analysis Methods etc. have been employed/used to interpret the data. Agricultural finance is one of the important factors that plays a larger role in boosting agriculture production and productivity. In recent years, particularly after the Green Revolution, the Indian agricultural sector has expanded to improve the socio-economic conditions of farmers. As the Socio-economic development is measured by the economic indicators such as the Gross Domestic Product, (GDP) life expectancy, (LE) literacy, and employment (L&E) rates etc. Hence, this study helps to understand the bottlenecks of the agriculture and rural development banks so as to perform well with economic viability and aiding the farm community toward betterment of the agriculture where, it helps to measure economic condition of the farmers. Consequently, an attempt is made to gain insight into the issues of the federated agriculture and rural development banks of the country. Limitations of the study: Despite all efforts to make the analysis more exhaustive and scientific, a study of this nature is doomed to have some limitations as the study is purely based on the secondary data/statistics maintained by the different organizations of the concerned field and the data obtained may not always be the exact and accurate. The study is limited to the performance of the financial indicators of the banks only.

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growth and performance of SCARDB’S

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Abstract Allergy describes a constellation of clinical diseases that affect up to 30% of the world�s population. The underlying pathophysiology involves immunoregulatory dysfunctions similar to those noted in highly stressed populations. Histamine is a major mediator in allergic reactions and the histamine H1 receptor is responsible for many of the symptoms of allergic reactions such as rhinorrhoea, contraction of bronchial and gastrointestinal smooth muscle, and many forms of itch. H1 receptor antagonists are used extensively for the treatment of allergic disorders to the extent that "anti-histamines" would be universally recognized as a treatment for hayfever, for example, but not for asthma. This work aims to find the binding sites between the phytochemicals from coleus barbatus and the human histamine h1 receptor protein. The protein 3D structure is retrieved from the PDB database. The active sites of the histamine h1 protein are derived from Castp. Binding molecules or ligands are derived from the literature and phytochemical databases. From PubChem, the 2D structures of the ligands are taken. Molecular docking is done by swissdock server and the final ADMET studies are done with the help of SwissADME. It is observed that alpha-ionone shows the best docking result among all the phytochemicals and also obeys the Lipinski rule of 5 and ADMET.

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Keywords: Allergy, histamine h1 receptor protein, PDB, PubChem, Cast p, Swissdock, Swiss ADME, Lipinski rule of five.

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A micro strip filter is an electronic filter that uses micro strip transmission lines to create circuitry that selectively leaves or blocks certain frequency signals. It is a passive device commonly used in communications, radar, and other electronic systems to reduce unwanted signals or noise and improve the quality of desired signals. The filter works by combining the effects of distributed capacitance, inductance and resistance in the micro strip transmission line and the placement of resonators such as capacitors or coils to create bandpass, low pass or high pass. Micro strip filters can be designed with narrow or wide bandwidth, high or low insertion loss, and high or low attenuation. They are compact and lightweight, allowing easy integration into printed circuit boards (PCBs) or other circuits. By applying a high frequency microwave signal, its h-parameter, s-parameter, y-parameter, z-parameter and Smith diagram are investigated. For this, we used 3 software HFSS, CST and IE3D. The results are consistent with almost any software.

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HFSS,CST,IE3D,Microstrip filter etc

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This is a document made on the basis of research that will provide important and innovative designs of machines and weapons, important formulas related to astronomy and physics along with the hypothesis of new atomic model.

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Machine, Innovation, Astronomy, Physics, Weapons, Atom

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Creative Commons Attribution 4.0 and The Open Definition

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This paper seeks to investigate into the to study the Traditional Circular structures in India both religious and habitable space structures and to find out their thermal performance in various regions.To find out the historic background reason behind the circular structures in those earlier days. This study proceeds to analyze the detailed field data collected, with a view to identify the indoor thermal environment with respect to outdoor thermal environment in different regions. There is a regression analysis to obtain information about the thermal environment of different traditional and modern residential buildings with different conditions.To investigated the existing circular earthen buildings that have performed well in seismic activities, and noted their features compared with other earthen buildings. The paper concludes that, thermal performance of which is better the circular building or other geometrical shape - square ,rectangle shape buildings.To find out the daylight factor inside the building of both Circular and square/rectangular shape building.

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Traditional Circular temples in Tamilnadu , Daylight simulation for Circular building

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

BACKGROUND: Police officers are often overlooked as valued protectors of society. They experience difficulties from superiors, citizens, and even their uniforms, causing physical injury, discomfort, and mental repercussions. Musculoskeletal diseases are one of the major health problems related to work in different professions among which, the police activity stands out due to their physically demanding character. There is a potential negative impact due to high work pace with little recovery time, work place violence and multiple shifts affecting not only physical but also mental health of the working officers. Some research indicate that this occupational group has a three times greater risk of being injured at work than all other occupations. OBJECTIVE: The primary objective is to study the most prevalence area of musculoskeletal pain in police officers also to find out the prevalence of working factors and non-working factors influencing the musculoskeletal pain. MATERIALS AND METHOD: 40 police officers from Loni and Rahata police station were selected based on the inclusion and exclusion criteria. Data was collected using the Nordic Musculoskeletal Questionnaire (NMQ) and a self-administered pain questionnaire. RESULTS: WORKING FACTORS INFLUENCING MUSCULOSKLETAL PAIN: Data from 40 participants was analyzed. Out of 40 participants 52% did desk job whereas 42.5% spend their day on bike, 40% worked on ground and 22% spend their day in a vehicle(car/van) majority of times. It was reported that (75%) complained that they did not get adequate sleep with (72.5%) participants claiming their job to be stressful in nature. According to the participants past year experience noted, (77.5%) were exposed to disturbing crime, (15%) were exposed to catastrophic loss and (12.5%) were exposed to fight during their service. NON- WORKING FACTORS INFLUENCING MUSCULOSKLETAL PAIN: (32.5%) of the participants were reported to have family stress. Approximately (22.5%) of the participants reported being addicted to tobacco chewing whereas (20%) and (7.5%) being addicted to alcohol and smoking respectively. NORDIC PAIN QUESTIONNAIRE : In this study, the upper back (45%), lower back (45%) and knees (45%) were the most commonly affected body regions in the past 12 months. The knees (35%) were the most common body region affected in the past 7 days which was followed by lower back pain (30%) and upper back pain by (25%). CONCLUSION: Out of the 40 participants evaluated for this study and according to the questionnaire evaluated it shows that there was a high 12-month prevalence of musculoskeletal pain among the police officers with upper back, lower back and knees being the most commonly reported body region. ?

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police officers, musculoskeletal pain, prevalence, musculoskeletal disorders

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Creative Commons Attribution 4.0 and The Open Definition

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The challenge of incorporating Artificial Intelligence (AI) into enterprises persists despite growing interest. According to recent analyses, up to 85% of AI programmes eventually fall short of their goals. There are still few studies on successful AI applications, which might provide businesses just starting their AI journeys useful insights. In order to provide value to corporate management, this research tries to understand the proper business management of AI technology, people, and processes. This article goes into further detail about the resource orchestration strategy and examines how effectively AI is being used in Taobao’s e-commerce fulfilment centre for business management. The results suggest that data, AI algorithms, and robots are the most important AI resources. These resources must be organized (e.g., leveraged, deployed) to cooperate with other pertinent resources, such as storage facilities and existing information systems, in order to develop significant AI capabilities. Learning, planning, and prediction are the three main AI capabilities. The capacity of AI to generate business value in terms of effectiveness (for example, labour productivity, space optimization), efficacy (for example, data analytics), and effectiveness for study and practise, the effects of comprehending these social informatics of AI are addressed for business management.

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Business management, Artificial intelligence, Resource orchestration, Smart warehouse, E-commerce, Fulfillment center.

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Creative Commons Attribution 4.0 and The Open Definition

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Fake news spreads like a virus these days. Mindless and incessant forwarding of WhatsApp messages without verifying the correctness of such messages is leading to the spread of fake news, and many a time, such messages assume racial and religious overtones. Therefore, dealing with these in real-time and in an accurate scale is a critical issue. Whatsapp made a few changes in the app for Indian users, like labeling forwarded messages, removing the quick forward button, and limiting the number of allowed forwards to five people or five groups at a time. It did stop the individual forwards carrying nonsense messages and fake news but it continues to revel in Whatsapp groups. Complete anonymity is one of the biggest problems with this menace of fake news. WhatsApp needs to take more concrete steps to ensure that each time a message is sent, it must have some indication of the sender’s identity. This would make it easier for the law enforcement agencies to get hold of the person who actually created the message. Our proposed system creates accountability for every user who shares a forwarded message, so as to make them think twice before sending an abusive message or forwarding fake news. Forwarded messages don’t have accountability, which leads to the problem of forwarding them too many times. So to stop this from happening, we have created a way of identifying the senders through a hash code, which can be found by selecting the message and clicking on the hash info option. This displays the hash code as well as the hash pointer for that message. By using this feature, every user knows that they will be held accountable whenever they forward a message. This can stop people from sending fake news and helps us to identify every person to which it has been sent as well as easy identification of the source. This feature also helps users to have a better overall user experience, as providing users with the ability to stop the propagation of fake news helps them to trust the app more easily.

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WhatsApp , Fake News, Hash Info, Security, Context aware, Intelligence, Progressive, Accountability.

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Creative Commons Attribution 4.0 and The Open Definition

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This study investigates the impact of various Career Development Practices undertaken in organizations on Employee Retention. For an HR, these practices are crucial because they are in charge of employee development and advancement. The better opportunities and career development practices they offer to their employees the more productivity employees will bring to the organization. Career Development refers to advancement in career-building opportunities for every individual. In a workplace, it assists the employees to overcome hindrances and any kind of challenges that they may face while working towards achieving their goals. These practices are gaining importance in today�s day and age because employees are looking beyond just pay and compensation and are looking forward to bridging the gap between their skills and opportunities. As a student, or as a fresher who is ready to step out in the world, this study will provide insight into how employee career development programs and practices have an effect on the decision of employees to leave or to get retained in the organization. In the longer run, people prefer a life and job that not only pays them well but also helps to maintain work-life balance and long-term career goals. These career development goals help them to think for the future in a precise manner and hence are essential. This study will specifically anchor the result of the career development practices on employee retention and gain insight into whether these practices work out employee retention in the context of the real world.

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Career Development, Employee Retention, Mentoring, Career Advancement practices

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Creative Commons Attribution 4.0 and The Open Definition

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In this work, we present the design and characterization of Green Fluorescent Protein (GFP) based reporter systems designed to describe cellular activity in �complex,� heterogeneous bioreactors. The reporter systems consist of Escherichia coli strains carrying growth dependent promoters fused to genes expressing stable and unstable variants of GFP, respectively. The response of Eschcrichia coli cells to transient exposure to glucose was studied in a two- compartment scale down bioreactor (SDR) consisting of a well-stirred tank reactor (STR) connected to a plug-flow reactor (PFR). Such a SDR system is employed to mimic the situation of high glucose concentration and oxygen limitation that often encountered in large-scale, fed- batch bioreactors and the response of E. coli was simulated by continuously pumping microbial cells from STR to the PFR. We found that repeated addition of concentrated glucose pulses with varied frequency at the entrance of the PFR had consequenc on strain physiological behavior. The GFP expressions were significantly marked after 10 h of cultivation in STR (control reactor) and SDR, whereas, growth rates were rather similar. Additional experiments in chemostat with programmed glucose perturbation suggested that the activities of the promoters were linked with the substrate limitation signal. Taken together with immunoblot analysis. we suppose protein leakage is responsible for the overexpression of/Is and the related promoters, such as rrnB in this case study. but additional works are required in order to confirm this relationship. This investigation is useful for a better understanding of the fast dynamic phenomena occurring in heterogeneous large-scale bioreactors.

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Destabilized GFP. Scale down, Heterogeneity, Escherichia coil

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Abstract : Covid-19 belongs to the family of Coronaviridae which has several variants like SARS, MERS, Omicron etc. that have the ability to spread infection. This is zoonotic infection. It can mainly affect the lungs or other respiratory parts. Some clinical trials are performed (Hong kong trial, Italian trial) for the analysis of the medicines/ treatment which one is more effective for covid-19 treatment. Detecting methods are also available for the confirmation of covid-19 infection. After detection and case study analysis, we observe that the homeopathic treatment is best for covid-19 infection alerts.

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Keywords : Covid-19, SARS, MERS, Zoonotic, Treatment, Homeopathy, Allopathy.

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Creative Commons Attribution 4.0 and The Open Definition

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Work life balance is the term used to describe the situation in which an individual has successfully managed to balance their work life demands with the needs of their personal life. In short, WLB has numerous positive effects including less stress, a lower risk of burnout & a greater sense of well- being.

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Creative Commons Attribution 4.0 and The Open Definition

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less stress, burnout

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Pantoprazole (Protonix) is an irreversible proton pump inhibitor (PPI) that reduces gastric acid secretion. In combination with two antimicrobial agents (most commonly metronidazole, clarithromycin or amoxicillin) for 6-14 days, pantoprazole 40 mg twice daily produced Helicobacter pylori eradication rates of 71-93.8% (intent-to-treat [ITT] or modified ITT analysis) in patients without known antibacterial resistance. Pantoprazole-containing triple therapy was at least as effective as omeprazole- and similar in efficacy to lansoprazole-containing triple therapy in large trials. In the treatment of moderate to severe gastro-oesophageal reflux disease (GORD), oral pantoprazole 40 mg/day was as effective as other PPIs (omeprazole, omeprazole multiple unit pellet system, lansoprazole and esomeprazole) and significantly more effective than histamine H(2)-antagonists. Pantoprazole 20 mg/day provided effective mucosal healing in patients with GORD and mild oesophagitis. Intravenous pantoprazole 40 mg/day can be used in patients who are unable to take oral medication. Oral pantoprazole 20-40 mg/day for up to 24 months prevented relapse in most patients with healed GORD. According to preliminary data, oral pantoprazole 20 or 40 mg/day was effective at healing and preventing non-steroidal anti-inflammatory drug (NSAID)-related ulcers, and intravenous pantoprazole was at least as effective as intravenous ranitidine in preventing ulcer rebleeding after endoscopic haemostasis. Oral or intravenous pantoprazole up to 240 mg/day maintained target acid output levels in most patients with hypersecretory conditions, including Zollinger-Ellison syndrome. Oral and intravenous pantoprazole appear to be well tolerated in patients with acid-related disorders in short- and long-term trials. Tolerability with oral pantoprazole was similar to that with other PPIs or histamine H(2)-antagonists in short-term trials. Formal drug interaction studies have not revealed any clinically significant interactions between pantoprazole and other agents. In conclusion, pantoprazole is an effective agent in the management of acid-related disorders. As a component of triple therapy for H. pylori eradication and as monotherapy for the healing of oesophagitis and maintenance of GORD, pantoprazole has shown similar efficacy to other PPIs and greater efficacy than histamine H(2)-antagonists. Limited data suggest that it is also effective in Zollinger-Ellison syndrome and in preventing ulcer rebleeding. Pantoprazole is well tolerated with minimal potential for drug interactions. The availability of pantoprazole as both oral and intravenous formulations provides flexibility when the oral route of administration is not appropriate. Thus, pantoprazole is a valuable alternative to other PPIs in the treatment of acid-related disorders

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Pharmacovigilance pantoprazole OMEPRAZOL

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An attempt has been made in the present study to predict the default occurrence of selected pharmaceutical sector firms using MDA, Logit function and structural model. Study developed 2 models using MDA and Logit model, further study also evaluated the Altman original model and calibrated model by applying it on sample data of selected textile sector. The developed models have also been validated on the out-of-sample data. The study obtained satisfactory statistical results pertaining to the MDA and Logit developed models but not from Structural Model and Altman Z score model. Additionally, the classification results witnessed the following accuracies for MDA, Calibrated, Altman, Logit and Structural model such as 88%, 80%, 19%, 90% and 25%. The validation accuracies obtained by mda, calibrated and logit models are 37%, 37% and 92%.

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Altman Z score, Multiple Discriminant Analysis, Logistic Regression, Structural Model, Default Prediction, Bankruptcy Prediction, NPA, and Corporate Default.

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 Abstract

Pharmacovigilance (PV) plays a key role in the healthcare system through assessment, monitoring and discovery of interactions amongst drugs and their effects in humans. Pharmaceutical and biotechnological medicines are designed to cure, prevent or treat diseases; however, there are also risks particularly adverse drug reactions (ADRs) can cause serious harm to patients. Thus, for safety medication ADRs monitoring is required for each medicine throughout its life cycle, during development of drugs such as pre-marketing including early stages of drug design, clinical trials, and post-marketing surveillance. PV is concerned with the detection, assessment, understanding and prevention of ADRs. Pharmacogenetics and pharmacogenomics are an indispensable part of clinical research. Variation in the human genome is a cause of variable response to drugs and susceptibility to diseases are determined, which is important for early drug discovery to PV. Moreover, PV has traditionally been involved in mining spontaneous reports submitted to national surveillance systems. The research focus is shifting toward the use of data generated from platforms outside the conventional framework such as electronic medical records, biomedical literature, and patient-reported data in health forums. The emerging trend in PV is to link Premarketing data with human safety information observed in the post-marketing phase. The PV system team obtains valuable additional information, building up the scientific data contained in the original report and making it more informative. This necessitates an utmost requirement for effective regulations of the drug approval process and conscious pre and post approval vigilance of the undesired effects, especially in India.

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Keywords: Contraindications, Indications, Pain management, Tramadol

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Creative Commons Attribution 4.0 and The Open Definition

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Pharmacovigilance deals with safety & monitoring of drugs for the purpose of detection of frequency of adverse drug reaction to improve patients’ healthcare & safety. Adverse drug reactions have been a large-scale problem in developing countries which brings pharmacovigilance as a major field in drug manufacturing & development. Pharmacovigilance is aimed at increasing reporting rates and minimizing adverse drug reactions. As pharmacovigilance is concerned with toxicology studies of drugs this study deals with the account of isoniazid (referred as first line anti tubercular drug) This review is concerned with data collected about toxicology & account of isoniazid.

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Pharmacovigilance, toxicology, isoniazid, adverse drug reaction, clinical trials

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Medicines and vaccines have transformed the prevention and treatment of diseases. In addition to their benefits, medicinal products may also have side effects, some of which may be undesirable and / or unexpected. Pharmacovigilance is the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other medicine/vaccine related problem. All medicines and vaccines undergo rigorous testing for safety and efficacy through clinical trials before they are authorized for use. However, the clinical trial process involves studying these products in a relatively small number of selected individuals for a short period of time. Certain side effects may only emerge once these products have been used by a heterogenous population, including people with other concurrent diseases, and over a long period of time. Diclofenac, a nonsteroidal anti-inflammatory drug, is not a documented cause of rhabdomyolysis in the Summaries of Product Characteristics held by major regulators. Diclofenac is a medication used in the management and treatment of inflammatory conditions and pain. It is in the class of non-steroidal anti-inflammatory drugs (NSAID). This activity outlines the indications, mechanism of action, administration, adverse effect profile, contraindications, and other key factors for diclofenac in the clinical setting pertinent to healthcare team members to treat and manage patients with inflammation-related conditions.

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 Keywords

contraindications, indication , Efficacy, safety, pharmacokinetic of diclofenac .

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Pharmacovigilance promotes the safe and proper use of medications. Pharmacovigilance entails more than only assessing commercially available drugs and submitting this report to the national surveillance system. Pharmacovigilance efforts in India began far earlier than the launch of the country’s official pharmacovigilance programme (PVPI) In India, several scientists, doctors, and administrators contributed to the field of pharmacovigilance. Pharmacovigilance’s goal is to safeguard the public’s health by discovering, assessing, and limiting safety concerns to make sure that the benefits of all medications outweigh the risks. The drug rivastigmine is the main subject of pharmacovigilance, which has expanded from being a small activity in drug control to a large one. The medication aids in the safety of clinical trials, the efficacy of adverse drug reactions, the development of safety for correct usage, and the right communication of that information to a variety of relevant stakeholder groups. Clinical research requires pharmacogenomics and Pharmacogentics as essential components. This pharmacovigilance review is outlined in the current pharmacovigilance review article as objectives drugs parts of the non clinical and clinical safety specification, efficacy selection of medicines marketing and post marketing service surveillance report, and adverse drug reaction report.

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 Keywords

pharmacovigilance, Objectives, Types, Component, Clinical Research ,ICH guideline, Clinical and Non clinical Safety, Selection and Selling of drugs, Identify adverse drug reaction, Consumption report, ADR Monitoring Form

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Title: A Study to evaluate the effectiveness of balloon therapy on selected respiratory parameters among children with Acute respiratory tract infection in Dhanalakshmi Srinivasan Medical College and Hospital, Perambalur.Objective: To assess the level of acute respiratory tract infection before and after intervention in experimental and control group. To evaluate the effectiveness of balloon therapy on respiratory parameters among children with acute respiratory tract infection in experimental and control group. To find out the association between the post test level of respiratory parameters among children with acute respiratory tract infection with their selected demographic variables in experimental and control group. Hypothesis: There is a significant difference between the pre-test and post-test level of respiratory parameters among children with acute respiratory tract infection in experimental group and control group. There is a significant effectiveness of balloon therapy on respiratory parameters among children with acute respiratory tract infection in experimental and control group. There is a significant association between the post test level of balloon therapy on respiratory parameters with selected demographic variables between the experimental group and control group. Conceptual Frame Work: Nola.J.Pender�s Health Promotion Model (2002-Revised). Research Design: Quasi experimental factorial design. Setting: Patients in DSMCH, Perambalur. Sample: Sampling were totally 30 children with Acute Respiratory Tract Infection, 15 samples were split for Experimental Group and 15 samples were taken for Control group. Sampling Technique: Convenient sampling technique. Intervention: In Experimental Group 53% of them have age group with 6 to 8 years. 73% of the respondents from the female group. 40% of them type of family group are from joint family and nuclear family. 40% of them third child. 53% of them from rural locality. 47% of them were no prior infection. In Control Group 67% of them have age group with 6 to 8 years. 60% of the respondents from the female group. 53% of them type of family group are from joint family. 40% of them first child. 73% of them from rural locality. 60% of them were no prior infection. Result: After Intervention 53% of them have average level of Acute Respiratory Tract Infection. 33% of them Good improved level on Acute Respiratory Tract Infection after the intervention. 13% of them have poor improvement after intervention. Without Intervention There is no improvement Acute Respiratory Tract Infection. Conclusion: School age children�s with Acute Respiratory Tract Infection have only average and good level of socio activities. Balloon therapy was effective in improving level of activity like Respiratory parameters.

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COPD

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Creative Commons Attribution 4.0 and The Open Definition

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The Chanderi Hill Fort of Central India was built by Hindu Pratihar King Kirti Pal in 11th Century AD. It is also known as Kirti Fort in his name. The present Chanderi Township of Ashok Nagar district, M.P. was the capital of his reign. Earlier to Vedic period, the Chanderi region was ruled by King Shishupal, mentioned in Hindu Epic Mahabharata. It had been located strategically on the border of Malwa and Bundelkhand and connected Ancient Trade Route (ATR) from Central India to sea ports of Gujarat via. Malwa, Mewar, Deccan. The aim of study is multidisciplinary to elaborate the scientific interpretation of physical domain, terrain and landscape characteristics, correlation with the Histo-Archaeological, Architectural features of Hindu Arts and Cultural Heritages of Chanderi region and its tourism prospects. Under methodology, the Satellite Remote Sensing Imagery Data (2020-2021) have been utilized for demarcation of natural features and manmade physical structures, geomorphic, geologic units, settlement etc. and correlated with existing literatures records of the region. The study indicates that the Medieval Urban Settlement layout Plan of Chanderi Township evolved Ancient Hindu Vastushastra representing Vashtu Purusha Mandla with main axis orientation in stone walled fortified Ander Shahar (Inner Township). The Architectural Characteristics reveals the artistic carvings and decoration on Facades, Palaces, Havelis, Religeous Hindu Temples, Monuments shows mature Architectural style and Cultural Heritages of Medieval Rajputana period. The monuments including Kirti Fort, Havelis, Palace Badal Mahal, Gateways Mata Jageshwari Temple, religious places, Caves, reservoir of Rajghat dam etc. are major attractions for tourist and pilgrimages. Some effective protective measures are required under caretaking of professional environmentalist, archeologist, architects, historians with the help of NGO’s and public- participation of Chanderi Community. It will rise the Tourism Prospects of ancient cultural, religious heritage and Traditional Silk Trade Centre of Malwa region.

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KIRTI FORT, PRATIHAR KING, RANA SANGA, MEDIEVAL CENTRAL INDIA, BUNDELA ARCHITECTURE, CHANDERI SILK, MATA JAGESHWARI TEMPLE, VINDHYAN SANDSTONE, ANCIENT TOWN, TOURISM, MONUMENT, CAVE, BETWA RIVER, CONSERVATION, HERITAGES.

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Banking is one (if not the) most creative industry in the world, a biased opinion perhaps, but I believe apt for the question. Technology has provided another avenue for this creativity and it is just starting to be realized. Companies like Rocket Mortgage, Robinhood, Square, Ant Financial, etc. are providing a completely different view on what financial services are, and how they will be delivered. Beyond the pure technology is the impact that it is having on business models of banks and other financial services providers. Banks now make less than half of the mortgage loans in the US for example. The next phase of technology will likely be a little less obvious to consumers, as automation is applied to all types of processes and back office operations. Those companies and individuals with an understanding of technology and financial services will continue to change the way banking is considered Banking can�t survive today without technology. Needless to say, what technology has done to us and how easy the life has become. Let�s go back to the era where there were no ATM�s, can someway tell me how life was at that point of time and how life is today. The same goes for things that we can do online these days; I don�t remember going in the last 4 years. This has all happened because technology is playing a huge role in banking nowadays. You remove the word technology from banking and I can guarantee things will work but the banks will feel paralyzed. This is called impact.

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This particular paper is about the impact of technological operations in Public and Private Sector banks

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ABSTRACT A human life is divided into five main stages mainly infancy, childhood, adolescence, adulthood and old age. Among this early childhood is considered as one of the most important and precious time between the attainment of adulthood. The first five years of life are critical for child development and it entails the biological, psychological and emotional changes occur. During the development stage they require adequate nutrients which influencing the growth and immunity. If they are not fulfilled with adequate requirement they suffer from certain deficiency disorders. The ministry of health, government of India, central health council launch programs aimed at controlling or eradicating diseases which cause considerable morbidity and mortality in India. RESULT: The study reveals that knowledge regarding selected national child health scheme among general population in rural and urban areas at Nagpur district, 3% of general population had poor knowledge, 17% of general population had average knowledge, 48% 0f general population had good knowledge, 25% of general population had very good knowledge and 7% of general population had excellent knowledge. Chi square test is used to assess the association between level of knowledge and demographic variable that is age, gender, residence and source of information. Out of these demographic variable, residence is found to be significantly associated with the level of knowledge regarding selected national child health scheme. CONCLUSION: The study shows that the knowledge regarding selected national child health schemes among general population in rural and urban areas at Nagpur district and demographic variables, 3% of general population had poor knowledge, 17% of general population had average knowledge, 48% 0f general population had good knowledge, 25% of general population had very good knowledge and 7% of general population had excellent knowledge.

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scheme, child health, programs, knowledge, general population

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Asset Liability Management is one of the important process and the significant function through which the banks manage their balance sheet effectively. This helps the banks in mitigating their exposure to liquidity risk, interest rate risk, market risk, etc. and maximize the profitability of the bank. The job of ALM is carried out prudently by the ALCO of banks�. The significance of ALM increased with the deregulation of interest rates, increasing competition in the financial markets and the volatility in interest rates in the market. The present study is to analyse asset liability mismatches, emphasize how the Net Interest Income of top 7 public sector banks is impacted with interest rate changes and how the banks can manage their interest rate risk with the help of Gap Analysis. The study also includes sensitivity analysis for interest rate changes.

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Asset Liability Management, Gap Analysis, Interest rate risk, Net Interest Income

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ABSTRACT In December 2019, a new coronavirus (SARS-CoV-2) emerged, sparking an epidemic of acute respiratory syndrome (COVID-19) in humans, centred in Wuhan, China1. Within three months, the virus had spread to more than 118,000 cases and caused 4,291 deaths in 114 countries, leading the World Health Organization to declare a global pandemic. The pandemic has led to a massive global public health campaign to slow the spread of the virus by increasing hand washing, reducing face touching, wearing masks in public and physical distancing.(10) METHODOLOGY: This study was conducted on 100 general population at selected areas at Nagpur district. In this study, Non probability convenient sampling technique was used. Data regarding selected demographic variables are measured and recorded. RESULT:This study was revealed that out of 100 general population at selected areas at Nagpur district. In this study, Non probability convenient sampling technique was used. Data regarding selected demographic variables are measured and recorded. CONCLUSION:The study was done by using the tool self structured checklist to assess the impact regarding covid-19 pandemic on mental health among the general population.

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Impact of COVID-19, SARS, mental health, anxiety, depression, physical health, spiritual

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The performance of AWGN and Rayleigh fading channel with different subcarriers frequencies and channel capacity has been analyzed to show the BER performance indifferent condition. The performance clearly indicates the impact of our proposed system. It shows that the BER ratio may be decreased in case of increasing the channel subcarriers and the transmission strength is good. The performance of the multi-carrier transmission modulation scheme that uses multi-carrier transmission with OFDM have been analyzed with the BER ratio. The results show that that the increasing N can reduce the error and the channel strength is good. The results based on CFO have been considered also. It shows the degradation invoked by noise and non-ideal channel. Its shows the transmitting and receiving frequency mismatch and error chances can be recorded to show the system performance. In our case 16, 32, 64, 128, 256, 512 QAM based single carrier have been considered for CFO and 16, 32, 64 and 128 for BER performance.

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Keywords: BER, CFO, DWT, FFT, ICI, IDWT, IFFT, ISI, OFDM

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Wildlife has been considered as integral part of physical ecosystem being rich with her natural beauty and inherent some of the most rare species one can even found in the whole world. India in particular endows a rich account of wild life. This great natural resource comprises of about 8125 species of animals, among which 372 species of mammals, 1228 species of birds, 446 reptiles, 204 are amphibians, 2546 are fishes, 5050 are mollusks and 60383 are insects species.

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Wild Life, Mammals, Birds Insects, Species

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Creative Commons Attribution 4.0 and The Open Definition

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This paper critically analyses the procedural changes introduced by the amendment to the Juvenile Justice (Care & Protection of Children) Act, 2015 (hereinafter, the �Act�), effected in the aftermath of the Nirbhaya case. In particular, it will assess the import and scope of the amended sections 15, 18 through 21, read with other relevant provisions and rules of the Act. There emerge inadvertent legislative omissions in the amended Act that have resulted in a fatal anomaly, whereby the Juvenile Justice Board, which is presided over by a Magistrate First Class, is presently empowered to try a juvenile of- fender above the age of 16 and below 18, for heinous offences punishable by death. Crucially, no guidelines have been defined for the conduct of a �preliminary assessment� into the mental and physical capacity of the accused juvenile to commit the alleged heinous offence, nor any minimum standards or eligibility criterion prescribed for the qualification of the psychological �experts� whom the Magistrate is empowered to consult during the said assessment. Moreover, no such guidelines particular to the Indian context exist, nor have any qualification criterion for such psychological �experts� been prescribed by the various bodies governing psychological and psychiatric care, which are conspicuously silent on this subject. Furthermore, in cases where an offence is alleged under other special legislation such as the POCSO Act, there is a clash of jurisdiction. The exercise of power and jurisdiction u/S.15(2) of the JJ Act by a Presiding officer of the JJB necessarily results in the ouster of the jurisdiction of a designated Special Court of Session under POCSO Act, which is otherwise exclusively empowered to try POCSO offences directly impacting the quantum of sentence. This raises serious questions about arbitrariness, fundamental rights and due process, and grave doubts about the efficacy of the amendment.

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Juvenile Justice, Mental Capacity, Preliminary Assessment, Heinous Offence

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Climate change is causing a slew of challenges for the world .COVID-19, a newly developing zoonotic illness with likely bat origins that has infected millions of people and had severe global repercussions, was highlighted. For successful prevention and control of probable zoonosis, it is highly advised that One Health procedures be used. With a focus on the potential influence of climate change on natural animal and human systems, greater predictions and mitigations for how such consequences would vector born and zoonotic illnesses in humans and animals will be possible. Climate change has a number of negative consequences for agriculture, water resources, forests and biodiversity, health, coastal management, and temperature rise. Many helminthic, bacterial, viral, and protozoan parasitic diseases, as well as insect and ectoparasitic vectors that impact both animals and people, are affected by climate and weather.

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Climate change, vector born, zoonotic diseases, etiology

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Chronic neck pain is most common problem in people nowadays. Chronic neck pain can have causes such as working for hours over computer and mobile phones which eventually causes muscle strains.

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Chronic neck pain, VAS scale, NDI scale, college students

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Creative Commons Attribution 4.0 and The Open Definition

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Water is the second most significant requirement for life to exist after air. Accordingly, water quality has been depicted broadly in the logical writing. The most well-known meaning of water quality is "it is the physical, chemical, and biological parameter of water". This work undertaken as a water quality studies in urban lakes project to investigate the use of remote sensing in water quality studies. The lakes of study were chosen based on analyzing weightage ranking method. Among them polluted lakes were considered for the study. The main objective of the study is to Estimation of water quality parameters using satellite image and lab analysis. The water quality parameters are Turbidity (TU), Total suspended solids (TSS), pH, and Dissolved oxygen (DO). These parameters can indicate water quality of lakes and shows the distribution of pollutants. The project period at RRSC-South was from May � September 2022. The first part of this study involve the Prioritization of Bengaluru urban lakes for study of water quality, The selection of lakes was done by applying weightage ranking method. Also water samples were collected during field visit, lab analysis also done for collected samples with standard method. Then in second part of the study is selection of best band indexing from sentinel 2A MSI satellite image. In this part different band indexing were applied with lab analysis of each quality parameters to get best fit linear regression model, after getting suitable regression model water quality parameter estimated. Then RMSE, BIAS, MAPD are calculated and mapping done for each estimated Water quality parameters. So in this study by using Sentinel 2A MSI satellite image, Turbidity and Total suspended solid gives less than 60% accuracy, for pH and Dissolved oxygen gives more than 80% accuracy. As per this study sentinel 2A MSI satellite image is the suitable for the estimation of pH and Dissolved oxygen.

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Keywords: Water Quality, Band Index, Statistical Models, Regression Analysis, Reflectance, Sentinel-2 MSI.

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Vegetation extraction from remote sensing imagery is the process of extracting vegetation information by interpreting satellite images based on the interpretation elements such as the image colour, texture, tone, pattern and association information. The vegetation maps are critical for understanding biodiversity management and planning from local to global scales. There are two essential elements of vegetation maps that are based on classification of vegetation and spatial attribution of that classification. The difference between these vegetation cover can be done with using remote sensing and GIS. Remote sensing classification is an essential technique for mapping forest vegetation attributes like floristic composition, biomass, tree density etc. that addresses the considerable logistical challenge of measuring, mapping and monitoring across very large areas in an accurate, repeatable and cost-effective way. The most basic method is identifying plant communities or species is to create a vegetation map. Machine learning (ML) is a subdivision of artificial intelligence in which the machine learns from machine-readable data and information. It uses data, learns the pattern and predicts the new outcomes. Its popularity is growing because it helps to understand the trend and provides a solution that can be either a model or a product. This study is carried out to perform various machine learning algorithms for vegetation classification using remote sensing and ancillary spatial data across a heterogenous forest ecosystem in Virajpet Taluk, Kodagu district. The recently developed sentinel-2 satellite imagery holds great potential for improving the vegetation type classification at medium to large scales due to the concurrent availability of multispectral bands with high spatial resolution and quick revisit time. A study is classifying using Supervised classification, a type of machine learning technique. To perform the supervised classification, training samples have been generated using ARCGIS to run the spatial model in ERDAS software. The machine learning algorithm such as support vector machine (SVM), Random Forest (RF), k-Nearest Neighbour (k-NN), Navies Bayes and CART were used to classify. In terms of classification accuracy, a combination of these parameters was tested: The number of trees (NT), the variables per split (VPS) and the Bag Fraction (BF). Thus, this studies key contribution is classification of vegetation types and how the ML techniques are an efficient approach to map different land use and land cover classes, including different vegetation types and demonstrated that some algorithms perform this task with higher accuracy than the others. In our investigation, the RF algorithm chieved satisfactory results when compared with others and characterized with more accurate rate and less error rate.

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keywords: Multispectral bands, Random Forest, Machine Learning, SVM, Forest Classification.

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This paper describes Program Management activities in an aerospace industry is consolidated in the form of a document which happened during operational phase of a project. Proposal for workflow of Program management is also represented in this paper.

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Program management

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The widespread, colloquial understanding of the term �democracy� is �rule by majority�. So when was the last time any ruling party in India won a national �majority�? Never. Rule 64 of the Conduct of Election Rules, 1961, mandates that the winner of an election to a Parliamentary Constituency in the Lok Sabha shall be �the candidate with the most votes�. That is, a candidate with the �plurality� of votes is elected, which is distinct from a �major- ity� (50%+). This system of voting is colloquially referred to as �First Past the Post� (FPP). However, a significant number of candidates/parties fail to secure a true majority (50%+1) of votes even at the constituency level. Thus, a �majority� in Parliament is actually merely the aggregation of this constituency-level �plurality�. It does not constitute a majority of the overall votes polled at either the constituency level or the national level. On average, 51% of all constituencies in all general elections since 1962 returned candidates who did not secure a majority (50%+) of the votes in their own constituencies. Thus, constituencies have rou- tinely come to be represented by MP�s who were, themselves, not chosen by the majority. Or worse, rejected by the majority. Apart from the fact that FPP yields disproportionate results, the system also- - favours established political parties, - engenders corrupt practices - encourages �strategic voting� - incentivises divisive identity politics; - is incurably biased, - is prone to results that are unjustifiably incommensurate with the vote distribution - frequently �wastes� two thirds of the total vote. FPP infringes the fundamental right of freedom of expression through the ballot, impedes the constitutional right to effective representation and violates the cardinal principle of democ- racy, �rule by majority�. In so doing, FPP (Rule 64) is ultra vires Art.13, 14, 19(1)(a) and 21 of the Constitution of India.

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Public Choice, Plurality, Majority, Representation

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This Paper deals some generalized concepts on membrane behavior. Membrane classification and classification based on pore size are mentioned. Transport through the membrane is arranged in terms of active transport, passive transport, facilitated diffusion etc. Transport process driven by concentration gradient is cited with ion transport and concentration. A short accounts of Ultrafiltration, /Reverse-Osmosis, Nanofiltration processes are given. Factor affecting transport across membranes, membrane-solutioninteraction, time dependent flux, the concentration polarization, and mass transfer coefficient are discussed. Diffusion potential and applications of the membrane are included in this chapter. Various membrane processes, e.g. electrodialysis, piezodialysis, hemodialysis etc. are cited in this chapter. Polymers/ resins used for the membrane preparation are also mentioned.

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Membranes,Transport

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Creative Commons Attribution 4.0 and The Open Definition

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BACKGROUND: The chronic pain is define as the chronic lower back pain is established by the persistence of pain beyond 3 month of symptoms. The reason for chronic low back pain are multi factorial which include reduce physical activity, food habit, occupation, under lying disease. OBJECTIVE: This study aimed to evaluate the attitude and beliefs regarding physical activity and Exercise in patients who are suffering from chronic low back pain. METHOD: For this literature review, we used standard search strategies involving to quarrying of online data based MEDLINE (Pub med), Google scholar, Sci-hub and PEDRO using key words followed by evaluation of the relevant articles. we used key words �Chronic low back pain�, �Attitude and belief towards physical activity and exercise�. RESULT : We have reviewed 25 articles to understand the attitude and belief towards physical activity and exercise in patient with chronic low back pain. The people those who are having chronic low back pain are less active than the normal individual because chronic pain bother them to performed there physical activity. CONCLUSION: : Majority of available literature review suggest that patient with chronic low back pain often present dysfunctional beliefs and attitude in relation to pain. A large population subjects believed that they need to protect their back to prevent injury: Which shows that this belief may result in reduce confidence to use the back and contribute to fear avoidance.

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Chroniclowbackpain�,�Attitudeandbelieftowardsphysicalactivity and exercise

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